BAY-1436032
BAY-1436032 is a potent, orally bioavailable small molecule inhibitor that selectively targets pan-mutant IDH1 enzymes. It is utilized in preclinical research to investigate mutant IDH1-driven mechanisms in cancers such as glioma, with studies demonstrating its activity in both cellular assays and in vivo models.
Product Specifications
CAS Number
1803274-65-8
Product Name Alternative
BAY1436032, BAY-1436032, BAY 1436032, inhibit, Isocitrate Dehydrogenase (IDH), IsocitrateDehydrogenase, IsocitrateDehydrogenase (IDH), Isocitrate Dehydrogenase, IDH, IDH1, Inhibitor
Field of Research
Metabolism Research
Purity
99.38% (May vary between batches)
Solubility
DMSO:120 mg/mL (245.13 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.17 mM)
Smiles
C[C@H]1C[C@H] (CC (C) (C) C1) n1c (Nc2ccc (OC (F) (F) F) cc2) nc2cc (CCC (O) =O) ccc12
Molecular Formula
C26H30F3N3O3
Molecular Weight
489.53
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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