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Seletalisib

Seletalisib (UCB5857) is a highly selective PI3Kδ inhibitor with an IC50 of 12 nM. It is a valuable research tool for studying B-cell and immune cell signaling in vitro and has demonstrated efficacy in models of inflammatory and autoimmune diseases in vivo.

Product Specifications

CAS Number

1362850-20-1

Product Name Alternative

Inhibit, Inhibitor, PI3K, PI3Kδ, Phosphoinositide 3-kinase, Seletalisib, UCB5857, UCB-5857, UCB 5857

Field of Research

Signal Transduction

Purity

95.87% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:3.3 mg/mL (6.83 mM) ; DMSO:80 mg/mL (165.68 mM)

Smiles

[O-][n+]1cccc (c1) -c1nc2c (Cl) cccc2cc1[C@@H] (Nc1ncnc2cccnc12) C (F) (F) F

Molecular Formula

C23H14ClF3N6O

Molecular Weight

482.85

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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