LY2857785
LY2857785 is a potent, reversible, and competitive ATP-competitive inhibitor targeting CDK7, CDK8, and CDK9 with IC50 values of 246 nM, 16 nM, and 11 nM, respectively. This small molecule is a valuable research tool for studying transcriptional regulation and cell cycle progression in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
1619903-54-6
Product Name Alternative
Inhibitor, inhibit, LY 2857785, LY2857785, LY-2857785, Apoptosis, CDK7, CDK, CDK8, CDK9, Cyclin dependent kinase
Field of Research
Cell Biology
Purity
96.00% (May vary between batches)
Solubility
DMSO:10 mg/mL (22.29 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.23 mM)
Smiles
CC (C) c1n (C) nc2ccc (cc12) -c1ccnc (N[C@H]2CC[C@@H] (CC2) NC2CCOCC2) n1
Molecular Formula
C26H36N6O
Molecular Weight
448.6
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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