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GSK189254A

GSK189254A is a potent and selective histamine H3 receptor antagonist with high affinity for human and rat receptors. It is widely used in neuroscience research to investigate the role of H3 receptors in cognitive function, sleep-wake cycles, and energy homeostasis, employing both in vitro binding assays and in vivo behavioral models.

Product Specifications

CAS Number

720690-73-3

Product Name Alternative

Inhibit, GSK189254, GSK-189254, GSK189254A, GSK-189254A, GSK 189254, Human H3 receptor, Inhibitor, HistamineReceptor, Histamine Receptor, Mouse H3 receptor

Field of Research

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Purity

98.04% (May vary between batches)

Solubility

DMSO:24 mg/mL (68.29 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.69 mM)

Smiles

CNC (=O) c1ccc (Oc2ccc3CCN (CCc3c2) C2CCC2) nc1

Molecular Formula

C21H25N3O2

Molecular Weight

351.44

Storage Conditions

Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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