MI-503
MI-503 is a potent and selective Menin-MLL interaction inhibitor exhibiting an IC50 of 14.7 nM. It demonstrates significant anti-proliferative activity in human MLL-rearranged leukemia cell lines with GI values ranging from 250 to 570 nM, supporting its use in both in vitro and in vivo cancer research.
Product Specifications
CAS Number
1857417-13-0
Product Name Alternative
MI 503, MI503, MI-503, Inhibitor, inhibit, Epigenetic Reader Domain, EpigeneticReaderDomain, Menin-MLL, Histone Methyltransferase, HistoneMethyltransferase
Field of Research
Epigenetics & Chromatin
Purity
99.87% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.54 mM) ; DMSO:45 mg/mL (79.7 mM) ; H2O:Insoluble
Smiles
Cc1c (CN2CCC (CC2) Nc2ncnc3sc (CC (F) (F) F) cc23) ccc2n (Cc3cn[nH]c3) c (cc12) C#N
Molecular Formula
C28H27F3N8S
Molecular Weight
564.63
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
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