KIRA6
KIRA6 is a potent small molecule inhibitor of IRE1α RNase activity with an IC50 of 0.6 μM. Its ability to induce apoptosis makes it a valuable tool for studying endoplasmic reticulum stress pathways in both cellular and animal models of disease.
Product Specifications
CAS Number
1589527-65-0
Product Name Alternative
Inhibitor, Inositol requiring enzyme 1, IRE1, IRE1α, KIRA 6, KIRA6, KIRA-6, inhibit
Field of Research
Cell Biology
Purity
97.91% (May vary between batches)
Solubility
DMSO:5.2 mg/mL (10.03 mM) ; Ethanol:2 mg/mL (3.86 mM)
Smiles
CC (C) (C) c1nc (-c2ccc (NC (=O) Nc3cccc (c3) C (F) (F) F) c3ccccc23) c2c (N) nccn12
Molecular Formula
C28H25F3N6O
Molecular Weight
518.53
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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