Aticaprant
Aticaprant (CERC-501) is a highly potent and brain-penetrant kappa-opioid receptor (KOR) antagonist with a Ki of 0.807 nM. It is a valuable research tool for investigating KOR's role in stress-related behaviors, depression, and addiction in both in vitro and in vivo preclinical models.
Product Specifications
CAS Number
1174130-61-0
Product Name Alternative
CERC 501, CERC501, CERC-501, Aticaprant, Inhibitor, inhibit, Opioid Receptor, OpioidReceptor, LY 2456302, LY2456302, LY-2456302, κ-opioid receptor
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
99.53% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.56 mM) ; DMSO:100 mg/mL (238.95 mM)
Smiles
Cc1cc (C) cc (c1) [C@@H]1CCCN1Cc1ccc (Oc2ccc (cc2F) C (N) =O) cc1
Molecular Formula
C26H27FN2O2
Molecular Weight
418.5
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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