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Lumateperone Tosylate

Lumateperone tosylate (ITI-007) is a multifunctional small molecule acting as a potent 5-HT2A receptor antagonist, a serotonin transporter (SERT) blocker, and a dopamine D2 receptor modulator with presynaptic partial agonism and postsynaptic antagonism. It is utilized in preclinical research for investigating neuropsychiatric disorders, including schizophrenia and mood disorders, in both in vitro and in vivo models.

Product Specifications

CAS Number

1187020-80-9

Product Name Alternative

Dopamine Receptor, Dopamine, dopamine D1 receptor, DopamineReceptor, 5-HT2A, 5-HT2A antagonist, 5-HT Receptor, 5-hydroxytryptamine Receptor, 5HTReceptor, 5HT Receptor, Lumateperone, lumateperone Tosylate, inhibit, ITI007, ITI-007, ITI 007, Inhibitor, postsynaptic D2 receptor, Serotonin Receptor, presynaptic D2 receptor, SERT, schizophrenia

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

95.83% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.84 mM) ; DMSO:250 mg/mL (441.93 mM)

Smiles

Cc1ccc (cc1) S (O) (=O) =O.CN1CCN2C3CCN (CCCC (=O) c4ccc (F) cc4) CC3c3cccc1c23

Molecular Formula

C31H36FN3O4S

Molecular Weight

565.7

Storage Conditions

Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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