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LY2795050

LY2795050 is a potent and selective κ-opioid receptor (KOR) antagonist with an IC50 of 0.72 nM. This compound is a valuable research tool for investigating KOR function in both in vitro assays and in vivo models related to addiction, pain, and mood disorders.

Product Specifications

CAS Number

1346133-08-1

Product Name Alternative

Central nervous system dysfunction, Inhibitor, inhibit, LY2795050, LY-2795050, LY 2795050, OpioidReceptor, Opioid Receptor, κ-opioid receptor, κκ-receptor, sex differences

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

96.50% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.9 mM) ; DMSO:50 mg/mL (122.58 mM)

Smiles

NC (=O) c1ccc (Oc2ccc (CN3CCC[C@H]3c3cccnc3) cc2) c (Cl) c1

Molecular Formula

C23H22ClN3O2

Molecular Weight

407.89

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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