JNJ-40411813
JNJ-40411813 (ADX-71149) is a positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R) with an EC50 of 147 nM. This compound is a valuable research tool for investigating mGlu2R function in neuropsychiatric disorders, facilitating both in vitro binding studies and in vivo behavioral experiments.
Product Specifications
CAS Number
1127498-03-6
Product Name Alternative
Inhibitor, JNJ40411813, JNJ-40411813, JNJ 40411813, inhibit, mGluR2, mGluR, Metabotropic glutamate receptors, ADX71149, ADX-71149, ADX 71149
Field of Research
Neuroscience
Purity
99.57% (May vary between batches)
Solubility
DMSO:24 mg/mL (69.59 mM)
Smiles
CCCCn1ccc (N2CCC (CC2) c2ccccc2) c (Cl) c1=O
Molecular Formula
C20H25ClN2O
Molecular Weight
344.88
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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