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AZ505

AZ505 is a potent and selective small molecule inhibitor of SMYD2, exhibiting an IC50 of 0.12 μM. It serves as a valuable chemical probe for investigating SMYD2's role in cancer biology and epigenetics, enabling target validation in both cellular and animal models of disease.

Product Specifications

CAS Number

1035227-43-0

Product Name Alternative

AZ 505, AZ505, AZ-505, Histone Methyltransferase, HistoneMethyltransferase, Inhibitor, inhibit, SMYD2

Field of Research

Epigenetics & Chromatin

Purity

98.18% (May vary between batches)

Solubility

DMSO:145 mg/mL (251.06 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.66 mM)

Smiles

Oc1ccc (CCNCCN (C2CCCCC2) C (=O) CCNCCc2ccc (Cl) c (Cl) c2) c2OCC (=O) Nc12

Molecular Formula

C29H38Cl2N4O4

Molecular Weight

577.54

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

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