LDN-192960
LDN-192960 is a potent, dual-kinase inhibitor targeting Haspin (IC50 = 10 nM) and DYRK2 (IC50 = 48 nM) . This cell-permeable compound is a valuable chemical probe for studying mitosis, cell cycle regulation, and DNA damage response in cellular and biochemical assays.
Product Specifications
CAS Number
184582-62-5
Product Name Alternative
DYRK2, DYRK, Dual specificity tyrosine phosphorylation regulated kinase, Dual specificity tyrosine regulated kinase, inhibit, Haspin, Haspin Kinase, HaspinKinase, Inhibitor, LDN 192960, LDN192960, LDN-192960
Field of Research
Cell Biology, Signal Transduction
Purity
98.01% (May vary between batches)
Solubility
MeOH:1 mg/mL (3.04 mM) ; DMSO:5.5 mg/mL (16.75 mM)
Smiles
Cl.Cl.COc1ccc2nc3ccc (OC) cc3c (SCCCN) c2c1
Molecular Formula
C18H20N2O2S
Molecular Weight
328.43
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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