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Amifostine thiol dihydrochloride

Amifostine thiol dihydrochloride (WR-1065) is a cytoprotective agent that activates p53 via a JNK-dependent pathway. It is widely used in research to investigate radioprotection and chemoprotection in normal tissues during in vitro and in vivo oncology studies.

Product Specifications

CAS Number

14653-77-1

Product Name Alternative

WR1065, WR-1065, WR 1065, p53, inhibit, Inhibitor, MDM-2/p53, Amifostine thiol, Amifostine thiol dihydrochloride, Amifostine thiol Dihydrochloride

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

95.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4.83 mM) ; DMSO:24 mg/mL (115.85 mM) ; H2O:100 mg/mL (482.71 mM)

Smiles

Cl.Cl.NCCCNCCS

Molecular Formula

C5H16Cl2N2S

Molecular Weight

207.165

Storage Conditions

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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