Tesevatinib
Tesevatinib (XL-647) is an orally bioavailable, multi-targeted tyrosine kinase inhibitor. It potently inhibits EGFR, ErbB2, KDR, Flt4, and EphB4 with low nanomolar IC50 values. This compound has been utilized in preclinical research for studying cancers and angiogenesis in both cellular and animal models.
Product Specifications
CAS Number
781613-23-8
Product Name Alternative
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.89% (May vary between batches)
Solubility
DMSO:45 mg/mL (91.58 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.07 mM)
Smiles
COc1cc2c (Nc3ccc (Cl) c (Cl) c3F) ncnc2cc1OC[C@H]1C[C@H]2CN (C) C[C@H]2C1
Molecular Formula
C24H25Cl2FN4O2
Molecular Weight
491.39
Storage Conditions
Store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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