Zimlovisertib
Zimlovisertib (PF-06650833) is a potent, selective, and orally bioavailable IRAK4 inhibitor, demonstrating low nanomolar IC50 values in cellular assays. It is a valuable research tool for investigating IRAK4's role in oncology, autoimmune, and inflammatory diseases, with utility in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1817626-54-2
Product Name Alternative
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
98.01% (May vary between batches)
Solubility
DMSO:150 mg/mL (415.09 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.07 mM)
Smiles
O (C[C@@H]1[C@H] (CC) [C@H] (F) C (=O) N1) C=2C3=C (C=C (C (N) =O) C (OC) =C3) C=CN2
Molecular Formula
C18H20FN3O4
Molecular Weight
361.37
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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