PAP-1
PAP-1 is a potent and selective small molecule inhibitor of the Kv1.3 potassium channel, exhibiting an EC50 of 2 nM and oral bioavailability. Its research applications include in vitro electrophysiology studies and in vivo models for investigating T cell-mediated autoimmune diseases, such as multiple sclerosis and type-1 diabetes.
Product Specifications
CAS Number
870653-45-5
Product Name Alternative
5- (4-Phenoxybutoxy) psoralen, Inhibitor, PAP 1, PAP-1, PAP1, KcsA, Kv1.3 channels, inhibit, Potassium Channel, PotassiumChannel
Field of Research
Pharmacology & Drug Discovery
Purity
99.35% (May vary between batches)
Solubility
DMSO:50 mg/mL (142.71 mM) ; H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.71 mM)
Smiles
O=c1ccc2c (OCCCCOc3ccccc3) c3ccoc3cc2o1
Molecular Formula
C21H18O5
Molecular Weight
350.36
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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