14-Deoxy-11,12-didehydroandrographolide
14-Deoxy-11,12-didehydroandrographolide (AP10) is a bioactive diterpenoid known for its ability to suppress NF-κB activation. This mechanism underpins its research applications in studying hypertension, inflammation, asthma, and cancer, with utility in both cellular and animal model experiments.
Product Specifications
CAS Number
42895-58-9
Product Name Alternative
14-dehydro Andrographolide, 14Deoxy11,12didehydroandrographolide, 14-Deoxy-11,12-didehydroandrographolide, 14 Deoxy 11,12 didehydroandrographolide, AP10, AP-10, AP 10, Inhibitor, inhibit, Nuclear factor-kappaB, Nuclear factor-κB, NFκB, NF-κB, NF-kB, NFkB
Field of Research
Signal Transduction
Purity
98.55% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.02 mM) ; DMF:100 mg/mL (300.82 mM)
Smiles
CC1 (CO) C (O) CCC2 (C) C (CCC3=CCOC3=O) C (=C) CCC12
Molecular Formula
C20H28O4
Molecular Weight
332.43
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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