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Imipramine hydrochloride

Imipramine HCl is a tricyclic antidepressant that potently inhibits serotonin and norepinephrine reuptake. It is also reported to suppress extracellular vesicle release by inhibiting acid sphingomyelinase translocation, making it a useful research tool for studying neurotransmission and vesicular trafficking in cellular and animal models.

Product Specifications

CAS Number

113-52-0

Product Name Alternative

5-HTT, Imipramine, Imipramine (hydrochloride), Imipramine HCl, Imipramine hydrochloride, Imipramine Hydrochloride, inhibit, Inhibitor, Melipramine, G 22355, G22355, G-22355, SERT, Serotonin Transporter, SerotoninTransporter, serotonin, Tofranil, SLC6A4

Field of Research

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Purity

99.65% (May vary between batches)

Solubility

DMSO:100 mg/mL (315.59 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.62 mM) ; H2O:100 mg/mL (315.59 mM)

Smiles

CN (C) CCCN1c2ccccc2CCc2ccccc21.Cl

Molecular Formula

C19H25ClN2

Molecular Weight

316.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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