HPGDS inhibitor 2
GSK-2894631A is a potent and selective inhibitor of hematopoietic prostaglandin D synthase (h-PGDS), exhibiting an IC50 of 9.9 nM. This small molecule is a valuable research tool for investigating the role of PGD2 in allergic inflammation, asthma, and other immune-mediated conditions in both cellular and animal models.
Product Specifications
CAS Number
2101626-26-8
Product Name Alternative
Inhibit, GSK-2894631A, hPGDS, HPGDS inhibitor 2, HPGDS inhibitor2, HPGDS inhibitor-2, Inhibitor, Prostaglandin E synthase, PGESynthase, PGE synthase, PGE Synthase
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
99.60% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.57 mM) ; DMSO:130 mg/mL (343.54 mM)
Smiles
CC (C) (O) [C@H]1CC[C@@H] (CC1) NC (=O) c1cnc2cc (OC (F) F) ccc2c1
Molecular Formula
C20H24F2N2O3
Molecular Weight
378.41
Storage Conditions
-20°C
Notes
For research use only.
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