Methotrexate disodium
Methotrexate disodium is a potent inhibitor of dihydrofolate reductase (DHFR), disrupting folate metabolism. It is widely used in cancer research, autoimmune disease models, and in vitro studies of cell proliferation, leveraging its ability to inhibit DNA synthesis in both experimental and therapeutic contexts.
Product Specifications
CAS Number
7413-34-5
Product Name Alternative
Reductase, WR19039 disodium, synthesis, RNASynthesis, RNA Synthesis, rheumatoid, Amethopterin disodium, ADCCytotoxin, ADC Cytotoxin, ADC Payload, Antifolate, Apoptosis, antineoplastic, arthritis, CL14377 disodium, DNA, DNASynthesis, DNA Synthesis, DNA/RNA Synthesis, Inhibitor, hDHFR (dihydrofolate reductase), leukemia, inhibit, immunosuppressant, Methotrexate disodium, Methotrexate, lymphoblastic
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.77% (May vary between batches)
Solubility
H2O:40 mg/mL (80.26 mM) ; DMSO:Slightly soluble
Smiles
[Na+].[Na+].CN (Cc1cnc2nc (N) nc (N) c2n1) c1ccc (cc1) C (=O) N[C@@H] (CCC ([O-]) =O) C ([O-]) =O
Molecular Formula
C20H20N8Na2O5
Molecular Weight
498.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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