GLX351322
GLX351322 is a potent and selective NADPH oxidase 4 (NOX4) inhibitor with an IC50 value of 5 μM. This small molecule is a valuable research tool for investigating the role of NOX4-derived reactive oxygen species in pathologies such as fibrosis, cancer, and diabetic nephropathy in both cellular and animal models.
Product Specifications
CAS Number
835598-94-2
Product Name Alternative
NADPH Oxidase, NADPHoxidase, inhibit, NOX4, NOX, Inhibitor, GLX 351322, GLX351322, GLX-351322
Field of Research
Immunology & Inflammation, Metabolism Research
Purity
99.70% (May vary between batches)
Solubility
DMSO:20 mg/mL (46.35 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.32 mM)
Smiles
CCOC (=O) c1c (NC (=O) CN2CCN (CC2) C (=O) c2ccco2) sc2CCCc12
Molecular Formula
C21H25N3O5S
Molecular Weight
431.51
Storage Conditions
-20°C
Notes
For research use only.
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