Ibrutinib deacryloylpiperidine
IBT4A is a potent and highly selective irreversible inhibitor of Bruton's tyrosine kinase (BTK), exhibiting an IC50 of 0.5 nM. It is a valuable research tool for studying BTK-dependent signaling pathways in both cellular and animal models of B-cell malignancies and autoimmune disorders.
Product Specifications
CAS Number
330786-24-8
Product Name Alternative
5- (4-phenoxyphenyl) -7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine, Btk, Bruton tyrosine kinase, Inhibitor, Ibrutinib deacryloylpiperidine, IBT4A, inhibit
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.47% (May vary between batches)
Solubility
DMSO:10 mg/mL (32.97 mM)
Smiles
Nc1ncnc2[nH]nc (-c3ccc (Oc4ccccc4) cc3) c12
Molecular Formula
C17H13N5O
Molecular Weight
303.32
Storage Conditions
-20°C
Notes
For research use only.
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