DMNB
DMNB (6-Nitroveratraldehyde) is a small molecule inhibitor of DNA-dependent protein kinase (DNA-PK), a key enzyme in the non-homologous end-joining (NHEJ) DNA repair pathway, with an IC50 of 15 μM. It is used in research to study DSB repair mechanisms and to sensitize cells to DNA-damaging agents in both in vitro and in vivo models.
Product Specifications
CAS Number
20357-25-9
Product Name Alternative
Inhibit, Inhibitor, 6-Nitroveratraldehyde, dopaminergic systems, DMNB, DNA-PK, DNAPK, precursor, PET
Field of Research
Molecular Biology, Signal Transduction
Purity
97.87% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.47 mM) ; DMSO:22.5 mg/mL (106.55 mM)
Smiles
COC1=C (OC) C=C (C (C=O) =C1) [N+] ([O-]) =O
Molecular Formula
C9H9NO5
Molecular Weight
211.17
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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