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SR-717

SR-717 is a non-nucleoside STING agonist analog of cGAMP that stabilizes the protein in a closed, active conformation. It has demonstrated antitumor efficacy in preclinical models by enhancing immune cell activation and antigen cross-presentation in both cellular and animal studies.

Product Specifications

CAS Number

2375421-09-1

Product Name Alternative

SR 717, SR717, SR-717, STING, Stimulator of Interferon Genes, TMEM173, THP1, inhibit, ISG-THP1, MPYS, PD-L1, MITA, mimetic, immunity, Inhibitor, ERIS, cGAMP, antitumor

Field of Research

Immunology & Inflammation

Purity

98.24% (May vary between batches)

Solubility

DMSO:20 mg/mL (56.95 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (7.12 mM)

Smiles

[Li+].[O-]C (=O) c1cc (F) c (F) cc1NC (=O) c1ccc (nn1) -n1ccnc1

Molecular Formula

C15H8F2LiN5O3

Molecular Weight

351.19

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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