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K-Ras-PDEδ-IN-1

K-Ras-PDEδ-IN-1 is a high-affinity inhibitor (Kd = 8 nM) that targets the farnesyl-binding site of PDEδ, disrupting the K-Ras-PDEδ interaction. This tool compound is valuable for in vitro biochemical studies and cellular research exploring oncogenic Ras signaling pathways and potential therapeutic strategies.

Product Specifications

CAS Number

1841464-21-8

Product Name Alternative

Cancer, Inhibitor, K Ras PDEδ IN 1, inhibit, K-Ras-PDEdelta-IN-1, KRasPDEδIN1, K-Ras-PDEδ-IN-1, PDEδ, PDE, phosphodiesterase, Phosphodiesterase (PDE), pyrazolopyridazinone-based

Field of Research

Metabolism Research, Signal Transduction

Purity

99.48% (May vary between batches)

Solubility

DMSO:4.48 mg/mL (10.01 mM)

Smiles

Cc1ccc (cc1) -n1cc2c (C) nn (CCCC (=O) NCCc3ccc (F) cc3) c (=O) c2n1

Molecular Formula

C25H26FN5O2

Molecular Weight

447.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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