K-Ras-PDEδ-IN-1
K-Ras-PDEδ-IN-1 is a high-affinity inhibitor (Kd = 8 nM) that targets the farnesyl-binding site of PDEδ, disrupting the K-Ras-PDEδ interaction. This tool compound is valuable for in vitro biochemical studies and cellular research exploring oncogenic Ras signaling pathways and potential therapeutic strategies.
Product Specifications
CAS Number
1841464-21-8
Product Name Alternative
Cancer, Inhibitor, K Ras PDEδ IN 1, inhibit, K-Ras-PDEdelta-IN-1, KRasPDEδIN1, K-Ras-PDEδ-IN-1, PDEδ, PDE, phosphodiesterase, Phosphodiesterase (PDE), pyrazolopyridazinone-based
Field of Research
Metabolism Research, Signal Transduction
Purity
99.48% (May vary between batches)
Solubility
DMSO:4.48 mg/mL (10.01 mM)
Smiles
Cc1ccc (cc1) -n1cc2c (C) nn (CCCC (=O) NCCc3ccc (F) cc3) c (=O) c2n1
Molecular Formula
C25H26FN5O2
Molecular Weight
447.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog