HM03
HM03 is a small molecule research compound that selectively inhibits the chaperone protein HSPA5 (GRP78) . This inhibition has demonstrated anticancer activity in cellular studies, making it a useful tool for investigating endoplasmic reticulum stress pathways in oncology research.
Product Specifications
CAS Number
500565-15-1
Product Name Alternative
Cancer, cell, inhibit, Inhibitor, Heat shock proteins, heat, HCT116, HM-03, HM03, HM 03, HSPA5, HSP, tumor, protein, shock
Field of Research
Metabolism Research, Signal Transduction
Purity
96.96% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.8 mM) ; DMSO:125 mg/mL (270 mM)
Smiles
COc1ccc2nc3cc (Cl) ccc3c (Nc3ccc (O) c (CN4CCN (C) CC4) c3) c2c1
Molecular Formula
C26H27ClN4O2
Molecular Weight
462.97
Storage Conditions
-20°C
Notes
For research use only.
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