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HM03

HM03 is a small molecule research compound that selectively inhibits the chaperone protein HSPA5 (GRP78) . This inhibition has demonstrated anticancer activity in cellular studies, making it a useful tool for investigating endoplasmic reticulum stress pathways in oncology research.

Product Specifications

CAS Number

500565-15-1

Product Name Alternative

Cancer, cell, inhibit, Inhibitor, Heat shock proteins, heat, HCT116, HM-03, HM03, HM 03, HSPA5, HSP, tumor, protein, shock

Field of Research

Metabolism Research, Signal Transduction

Purity

96.96% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.8 mM) ; DMSO:125 mg/mL (270 mM)

Smiles

COc1ccc2nc3cc (Cl) ccc3c (Nc3ccc (O) c (CN4CCN (C) CC4) c3) c2c1

Molecular Formula

C26H27ClN4O2

Molecular Weight

462.97

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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