BOT-64
BOT-64 is a cell-permeable benzoxathiole compound that acts as an IKK-2 inhibitor by targeting the Ser177 and Ser181 residues in its activation loop. This small molecule is used in research to study NF-κB signaling in cellular and animal models of inflammation and immune response.
Product Specifications
CAS Number
113760-29-5
Product Name Alternative
Inhibitor, I kappa B kinase, IkB, IkB/IKK, IKK, IKK2, inflammatory, IL-6, IκB kinase, IκB, inhibit, NF-κb, BOT 64, BOT64, BOT-64, RAW 264.7
Field of Research
Signal Transduction
Purity
98.08% (May vary between batches)
Solubility
DMSO:30 mg/mL (109.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.32 mM)
Smiles
CC1 (C) Cc2oc (=Nc3ccccc3) sc2C (=O) C1
Molecular Formula
C15H15NO2S
Molecular Weight
273.35
Storage Conditions
-20°C
Notes
For research use only.
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