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BOT-64

BOT-64 is a cell-permeable benzoxathiole compound that acts as an IKK-2 inhibitor by targeting the Ser177 and Ser181 residues in its activation loop. This small molecule is used in research to study NF-κB signaling in cellular and animal models of inflammation and immune response.

Product Specifications

CAS Number

113760-29-5

Product Name Alternative

Inhibitor, I kappa B kinase, IkB, IkB/IKK, IKK, IKK2, inflammatory, IL-6, IκB kinase, IκB, inhibit, NF-κb, BOT 64, BOT64, BOT-64, RAW 264.7

Field of Research

Signal Transduction

Purity

98.08% (May vary between batches)

Solubility

DMSO:30 mg/mL (109.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.32 mM)

Smiles

CC1 (C) Cc2oc (=Nc3ccccc3) sc2C (=O) C1

Molecular Formula

C15H15NO2S

Molecular Weight

273.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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