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TH1020

TH1020 is a potent and selective small molecule inhibitor of the TLR5/flagellin interaction, exhibiting an IC50 of 0.85 μM. This compound is a valuable research tool for investigating TLR5-mediated signaling in both cellular assays and animal models of inflammation and immunity.

Product Specifications

CAS Number

1841460-82-9

Product Name Alternative

TH1020, TH-1020, TH 1020, TLR5, TLR, protein-protein, Toll-like Receptor (TLR), TNF-α, inhibit, Inhibitor, interaction, flagellin, Bacterial

Field of Research

Immunology & Inflammation, Infectious Disease & Virology

Purity

99.23% (May vary between batches)

Solubility

DMSO:4.54 mg/mL (10.01 mM)

Smiles

C (c1ccccc1) n1c (Sc2ncnc3c4cccnc4sc23) nnc1-c1ccncc1

Molecular Formula

C23H15N7S2

Molecular Weight

453.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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