TH1020
TH1020 is a potent and selective small molecule inhibitor of the TLR5/flagellin interaction, exhibiting an IC50 of 0.85 μM. This compound is a valuable research tool for investigating TLR5-mediated signaling in both cellular assays and animal models of inflammation and immunity.
Product Specifications
CAS Number
1841460-82-9
Product Name Alternative
TH1020, TH-1020, TH 1020, TLR5, TLR, protein-protein, Toll-like Receptor (TLR), TNF-α, inhibit, Inhibitor, interaction, flagellin, Bacterial
Field of Research
Immunology & Inflammation, Infectious Disease & Virology
Purity
99.23% (May vary between batches)
Solubility
DMSO:4.54 mg/mL (10.01 mM)
Smiles
C (c1ccccc1) n1c (Sc2ncnc3c4cccnc4sc23) nnc1-c1ccncc1
Molecular Formula
C23H15N7S2
Molecular Weight
453.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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