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3- (2-Naphthalenyl) -1- (3-pyridinyl) -2-propen-1-one

DMU2105 is a potent and selective CYP1B1 inhibitor, exhibiting an IC50 of 10 nM for CYP1B1 versus 742 nM for CYP1A1. This small molecule is a valuable chemical probe for studying CYP1B1's role in steroid metabolism, chemical carcinogenesis, and in cancer cell resistance mechanisms in vitro.

Product Specifications

CAS Number

1031063-36-1

Product Name Alternative

3- (2-Naphthalenyl) -1- (3-pyridinyl) -2-propen-1-one, DMU2105, DMU-2105, CYP1B1

Field of Research

Metabolism Research

Purity

99.37% (May vary between batches)

Solubility

10% DMSO+90% Corn Oil:2 mg/mL (7.71 mM) ; DMSO:25 mg/mL (96.41 mM)

Smiles

C (=CC (=O) C=1C=CC=NC1) C2=CC3=C (C=C2) C=CC=C3

Molecular Formula

C18H13NO

Molecular Weight

259.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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