G5-7
G5-7 is an orally bioavailable, selective JAK2 inhibitor that suppresses JAK2-mediated EGFR (Tyr1068) and STAT3 phosphorylation. It has demonstrated potential for glioma research in both cellular and animal models, showing efficacy in inhibiting tumor growth and related signaling pathways.
Product Specifications
CAS Number
939681-36-4
Product Name Alternative
Cycle, Apoptosis, JAK2 inhibitor G5-7, JAK, JAK2, G57, G-5-7, G5-7, G5 7, Glioma, phase, STAT3
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.30% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (58.69 mM)
Smiles
CCOC (=O) N1C\C (=C\c2ccccc2F) C (=O) \C (C1) =C/c1ccccc1F
Molecular Formula
C22H19F2NO3
Molecular Weight
383.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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