MM-102 TFA
MM-102 TFA is a potent and selective inhibitor of the WDR5-MLL1 interaction (IC50 = 2.4 nM), disrupting the MLL1 histone methyltransferase complex and reducing H3K4me3 levels. Its application in research, including in vitro studies and somatic cell nuclear transfer models, facilitates the study of epigenetic reprogramming and MLL-fusion driven leukemias.
Product Specifications
CAS Number
1883545-52-5
Product Name Alternative
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation
Purity
99.30% (May vary between batches)
Solubility
DMSO:99 mg/mL (126.3 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.21 mM)
Smiles
OC (=O) C (F) (F) F.CCC (CC) (NC (=O) C (C) C) C (=O) N[C@@H] (CCCNC (N) =N) C (=O) NC1 (CCCC1) C (=O) NC (c1ccc (F) cc1) c1ccc (F) cc1
Molecular Formula
C37H50F5N7O6
Molecular Weight
783.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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