HALOFUGINONE LACTATE
Halofuginone lactate, a halogenated derivative of the natural compound febrifugine, is a potent and specific inhibitor of prolyl-tRNA synthetase (Ki=18.3 nM) . It suppresses type-I collagen synthesis and TGF-β activity, making it a valuable research tool for studying fibrosis, osteoarthritis, and related pathways in both cellular and animal models.
Product Specifications
CAS Number
82186-71-8
Product Name Alternative
DNA Synthesis, DNASynthesis, HALOFUGINONE LACTATE, HALOFUGINONE Lactate, prolyl-tRNA synthetase, RNASynthesis, RNA Synthesis, Smad, TGF-β/Smad, TGF-β, TGFβ, TGFbeta/Smad, TGF-beta, TGF-b/Smad, TGFbeta, TGFb
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Purity
99.02% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (44.57 mM)
Smiles
CC (O) C (O) =O.O=C1N (CC (C[C@@H]2NCCC[C@H]2O) =O) C=NC3=C1C=C (Cl) C (Br) =C3
Molecular Formula
C19H23BrClN3O6
Molecular Weight
504.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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