MSA-2
MSA-2 is a potent, orally bioavailable non-nucleotide STING agonist. Its non-covalent dimer binds STING with nanomolar affinity, inducing interferon-β secretion and demonstrating robust anti-tumor activity and immune memory in syngeneic mouse models, including synergy with anti-PD-1 therapy.
Product Specifications
CAS Number
129425-81-6
Product Name Alternative
MSA 2, MSA2, MSA-2, MPYS, immunity, inhibit, Inhibitor, MITA, ERIS, interferon-β, MC38, secretion, TMEM173, TNF-α, Stimulator of Interferon Genes, STING, tumor
Field of Research
Immunology & Inflammation
Purity
97.87% (May vary between batches)
Solubility
DMSO:255 mg/mL (866.4 mM) ;0.5% CMC-Na:12.5 mg/mL (42.47 mM)
Smiles
COc1cc2cc (sc2cc1OC) C (=O) CCC (O) =O
Molecular Formula
C14H14O5S
Molecular Weight
294.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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