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CRBN modulator-1

WUN29654 is a thalidomide-based CRBN modulator with a Ki of 0.98 μM and an IC50 of 3.5 μM. This small molecule is used in biochemical and cellular research to study targeted protein degradation and probe CRBN-dependent pathways in vitro.

Product Specifications

CAS Number

2407829-65-4

Product Name Alternative

CRBN modulator 1, CRBN modulator1, CRBN modulator-1, E3 ligase-recruiting Moiety, Ligands for E3 Ligase, LigandforE3Ligase, Ligand for E3 Ligase, inhibit, Inhibitor, WUN 29654, WUN29654, WUN-29654

Field of Research

Cancer Biology, Pharmacology & Drug Discovery

Purity

99.24% (May vary between batches)

Solubility

DMSO:3.25 mg/mL (10.02 mM)

Smiles

Oc1cc2C (=O) N (C3CCC (=O) NC3=O) C (=O) c3cccc (c1) c23

Molecular Formula

C17H12N2O5

Molecular Weight

324.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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