Capmatinib 2HCl.H2O
Capmatinib 2HCl.H2O is an orally active, potent c-Met (HGFR) kinase inhibitor. It is used in cancer research to study tumor growth and metastasis, demonstrating activity in both cellular assays and animal models of c-Met-dependent cancers.
Product Specifications
CAS Number
1865733-40-9
Product Name Alternative
SNU-5, S114, U-87MG, H441, Inhibitor, HGFR, orally active, NVP-INC280 2HCl.H2O, INCB28060 2HCl.H2O, INCB-28060 dihydrochloride, INC-280 2HCl.H2O, INC280 dihydrochloride, inhibit, cMet, c-Met, c-Met/HGFR, cMet/HGFR, Balb/c nu/nu mice, ATP competitive, Apoptosis, Capmatinib 2HCl.H2O, Capmatinib 2HCl.H-2O, Capmatinib dihydrochloride
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.77% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.97 mM) ; DMSO:30 mg/mL (59.6 mM)
Smiles
O=C (C1=C (F) C=C (C2=NN3C (N=C2) =NC=C3CC4=CC=C5N=CC=CC5=C4) C=C1) NC.Cl.O.Cl
Molecular Formula
C23H21Cl2FN6O2
Molecular Weight
503.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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