CP 424174
CP 424174 is a potent and orally bioavailable small molecule inhibitor that blocks the post-translational processing of IL-1β (IC50 = 210 nM), preventing the generation of mature cytokine. This action indirectly inhibits the NLRP3 inflammasome, making it a valuable tool for researching inflammatory pathways in both cellular assays and animal models.
Product Specifications
CAS Number
210825-31-3
Product Name Alternative
CP424174, CP-424174, CP 424174, inhibit, Inflammasome, IL-1β, IL Receptor, ILReceptor, NLRP3, NOD-like Receptor (NLR), Inhibitor
Field of Research
Immunology & Inflammation
Purity
96.01% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (60.71 mM)
Smiles
CC (C) c1cc (Cl) cc (C (C) C) c1NC (=O) NS (=O) (=O) c1cccc (c1) C (C) (C) O
Molecular Formula
C22H29ClN2O4S
Molecular Weight
452.99
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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