CCI-007
CCI-007 is a selective small molecule inhibitor targeting MLL-rearranged, CALM-AF10, and SET-NUP214 fusion-driven leukemias, demonstrating an IC50 of 3.5 μM in the MLL-r cell line PER-485. It serves as a valuable research tool for investigating the pathogenesis and therapeutic targeting of these aggressive leukemias in both cellular and animal models.
Product Specifications
CAS Number
939228-52-1
Product Name Alternative
SET-NUP214, CMYC, CALM-AF10, CCI 007, CCI007, CCI-007, Apoptosis, inhibit, MLL-r, Inhibitor, Histone Methyltransferase, HistoneMethyltransferase, HOXA9, MEIS1
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
97.61% (May vary between batches)
Solubility
10% DMSO+90% Saline:2 mg/mL (5.95 mM) ; DMSO:25 mg/mL (74.33 mM)
Smiles
CCOC (=O) COc1ccc (\C=C2\SC (N) =NC2=O) cc1OC
Molecular Formula
C15H16N2O5S
Molecular Weight
336.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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