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DTHIB

DTHIB is a potent small molecule inhibitor of HSF1 signaling. It robustly suppresses the HSF1-driven oncogenic transcriptional program and inhibits the proliferation of prostate cancer cells in vitro. This compound is a valuable research tool for investigating HSF1 pathway biology and cancer therapeutics.

Product Specifications

CAS Number

897326-30-6

Product Name Alternative

Cancer, anticancer, degradation, DTHIB, HSP, HSP70, HSP90, HSP27, HSF1, Heat shock proteins, nuclear, inhibit, Inhibitor, prostate

Field of Research

Metabolism Research, Signal Transduction

Purity

98.86% (May vary between batches)

Solubility

10% DMSO+90% Saline:2 mg/mL (6.46 mM) ; DMSO:25 mg/mL (80.73 mM)

Smiles

[O-][N+] (=O) c1cc (NC (=O) Nc2ccc (F) cc2) ccc1Cl

Molecular Formula

C13H9ClFN3O3

Molecular Weight

309.68

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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