DTHIB
DTHIB is a potent small molecule inhibitor of HSF1 signaling. It robustly suppresses the HSF1-driven oncogenic transcriptional program and inhibits the proliferation of prostate cancer cells in vitro. This compound is a valuable research tool for investigating HSF1 pathway biology and cancer therapeutics.
Product Specifications
CAS Number
897326-30-6
Product Name Alternative
Cancer, anticancer, degradation, DTHIB, HSP, HSP70, HSP90, HSP27, HSF1, Heat shock proteins, nuclear, inhibit, Inhibitor, prostate
Field of Research
Metabolism Research, Signal Transduction
Purity
98.86% (May vary between batches)
Solubility
10% DMSO+90% Saline:2 mg/mL (6.46 mM) ; DMSO:25 mg/mL (80.73 mM)
Smiles
[O-][N+] (=O) c1cc (NC (=O) Nc2ccc (F) cc2) ccc1Cl
Molecular Formula
C13H9ClFN3O3
Molecular Weight
309.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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