ML 254
ML254 is a selective, competitive mGlu5 receptor antagonist that binds at the MPEP allosteric site. It exhibits a clean off-target profile and suitable pharmacokinetic properties for in vivo studies, facilitating research into neurological disorders such as anxiety, addiction, and Fragile X syndrome in rodent models.
Product Specifications
CAS Number
1428630-86-7
Product Name Alternative
Inhibitor, inhibit, Metabotropic glutamate receptors, mGluR5, mGluR, ML254, ML-254, ML 254, Schizophrenia
Field of Research
Neuroscience
Purity
98.09% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (88.62 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.44 mM)
Smiles
CC1 (COC1) NC (=O) c1ccc (cn1) C#Cc1cccc (F) c1
Molecular Formula
C18H15FN2O2
Molecular Weight
310.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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