ML 254
ML254 is a selective, competitive mGlu5 receptor antagonist that binds at the MPEP allosteric site. It exhibits a clean off-target profile and suitable pharmacokinetic properties for in vivo studies, facilitating research into neurological disorders such as anxiety, addiction, and Fragile X syndrome in rodent models.
Product Specifications
CAS Number
1428630-86-7
Product Name Alternative
Inhibitor, inhibit, Metabotropic glutamate receptors, mGluR5, mGluR, ML254, ML-254, ML 254, Schizophrenia
Field of Research
Neuroscience
Purity
98.09% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (88.62 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.44 mM)
Smiles
CC1 (COC1) NC (=O) c1ccc (cn1) C#Cc1cccc (F) c1
Molecular Formula
C18H15FN2O2
Molecular Weight
310.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR14674014 96 Well
Rat Methylenetetrahydrofolate Reductase ELISA kit
Sign In for Pricing
View Details MBS6210457-01 0.1 mL
BRCA2 (Breast Cancer Type 2 Susceptibility Protein, Fanconi Anemia Group D1 Protein, FACD, FANCD1) (MaxLight 550)
Sign In for Pricing
View Details MBS6210457-02 5x 0.1 mL
BRCA2 (Breast Cancer Type 2 Susceptibility Protein, Fanconi Anemia Group D1 Protein, FACD, FANCD1) (MaxLight 550)
Sign In for Pricing
View Details