8-Azaadenosine
8-Azaadenosine is a potent small molecule inhibitor of ADAR1-mediated adenosine-to-inosine RNA editing. It effectively suppresses key oncogenic phenotypes in thyroid cancer models, including proliferation, 3D spheroid growth, and cell invasion, as demonstrated in vitro. This compound is a valuable research tool for studying RNA editing in cancer biology and metastasis.
Product Specifications
CAS Number
10299-44-2
Product Name Alternative
Editing, Cal62, ADAR1, Adenosinedeaminase, 8Azaadenosine, 8-Azaadenosine, 8 Azaadenosine, Adenosine Deaminase, Adenosine deaminase, inhibit, invasion, LIN28B, migration, Inhibitor, proliferation, thyroid, TPC1, RNA
Field of Research
Metabolism Research
Purity
99.39% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (18.64 mM) ; DMSO:245 mg/mL (913.4 mM)
Smiles
Nc1ncnc2n (nnc12) [C@@H]1O[C@H] (CO) [C@@H] (O) [C@H]1O
Molecular Formula
C9H12N6O4
Molecular Weight
268.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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