MRT68921 dihydrochloride
MRT68921 dihydrochloride is a potent and selective dual inhibitor of the autophagy-initiating kinases ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. This compound is a valuable chemical probe for investigating autophagy mechanisms in both cellular and in vivo models of cancer and neurodegenerative disease research.
Product Specifications
CAS Number
2080306-21-2
Product Name Alternative
Inhibitor, MRT 68921, MRT 68921 Dihydrochloride, MRT68921, MRT-68921, MRT68921 dihydrochloride, MRT68921 Dihydrochloride, MRT-68921 dihydrochloride, MRT-68921 Dihydrochloride, inhibit, Unc-51 like kinase, ULK, ULK2, ULK1
Field of Research
Cell Biology
Purity
98.91% (May vary between batches)
Solubility
H2O:33.33 mg/mL (65.68 mM) ; DMSO:2 mg/mL (3.94 mM)
Smiles
Cl.Cl.CN1CCc2cc (Nc3ncc (C4CC4) c (NCCCNC (=O) C4CCC4) n3) ccc2C1
Molecular Formula
C25H36Cl2N6O
Molecular Weight
507.499
Storage Conditions
-20°C
Notes
For research use only.
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