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NSC 617145

NSC 617145 is a selective small molecule inhibitor of WRN helicase, specifically blocking its ATPase activity while sparing exonuclease function. This compound is a valuable research tool for studying WRN's role in DNA repair and genome stability in cellular and biochemical assays.

Product Specifications

CAS Number

203115-63-3

Product Name Alternative

Strand, RNASynthesis, RNA Synthesis, Rad51, WRN helicase, WRN, double, DNASynthesis, DSB, DNA/RNA Synthesis, DNA Synthesis, chromosomal, breaks, abnormalities, ATPase, inhibit, NSC617145, NSC-617145, NSC 617145, NHEJ, Inhibitor, helicase

Field of Research

Cell Biology, Molecular Biology, Neuroscience

Purity

98.31% (May vary between batches)

Solubility

DMSO:6 mg/mL (15 mM)

Smiles

CC (C) (CN1C (=O) C (Cl) =C (Cl) C1=O) CN1C (=O) C (Cl) =C (Cl) C1=O

Molecular Formula

C13H10Cl4N2O4

Molecular Weight

400.04

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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