NSC 617145
NSC 617145 is a selective small molecule inhibitor of WRN helicase, specifically blocking its ATPase activity while sparing exonuclease function. This compound is a valuable research tool for studying WRN's role in DNA repair and genome stability in cellular and biochemical assays.
Product Specifications
CAS Number
203115-63-3
Product Name Alternative
Strand, RNASynthesis, RNA Synthesis, Rad51, WRN helicase, WRN, double, DNASynthesis, DSB, DNA/RNA Synthesis, DNA Synthesis, chromosomal, breaks, abnormalities, ATPase, inhibit, NSC617145, NSC-617145, NSC 617145, NHEJ, Inhibitor, helicase
Field of Research
Cell Biology, Molecular Biology, Neuroscience
Purity
98.31% (May vary between batches)
Solubility
DMSO:6 mg/mL (15 mM)
Smiles
CC (C) (CN1C (=O) C (Cl) =C (Cl) C1=O) CN1C (=O) C (Cl) =C (Cl) C1=O
Molecular Formula
C13H10Cl4N2O4
Molecular Weight
400.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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