MPP+ iodide
MPP+ iodide is a neurotoxic metabolite used to model Parkinson's disease, selectively destroying dopaminergic neurons via DAT externalization while internalizing SERT in serotonergic neurons. It is widely applied in neuroscience research to study neurodegenerative mechanisms, including autophagic cell death in vitro models like SH-SY5Y cells.
Product Specifications
CAS Number
36913-39-0
Product Name Alternative
Inhibitor, inhibit, MPP+, MPP+ iodide, MPP+ Iodide, neurotoxic, neurons, Mitochondrial Metabolism, MitochondrialMetabolism, Autophagy, complex, chain, dopaminergic, respiratory
Field of Research
Cell Biology, Metabolism Research
Purity
99.49% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (13.46 mM) ; H2O:100 mg/mL (336.55 mM) ; DMSO:135 mg/mL (454.35 mM)
Smiles
[I-].C=1C=CC (=CC1) C=2C=C[N+] (=CC2) C
Molecular Formula
C12H12IN
Molecular Weight
297.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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